NCT03263832

Evaluation of the Antibiofilmogramme Test During Orthopaedic Device-Related Infection

Demonstration of Clinical Value of Antibiofilmogramme Test for Monomicrobial S. Aureus Orthopaedic Device-Related Infection

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 45 (actual)
• Sponsor: BioFilm Control · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is an observational study that does not change routine care. The primary objective of this study is to investigate the correlation between the administration of an antibiotherapy able to prevent biofilm formation according to the results of the Antibiofilmogramme test, and the relapse of the infection for patient with orthopaedic device-related infection.

Detailed description

The secondary objectives are: A. Investigate the role of antibiogram-antibiofilmogramme concordance (in terms of S. aureus strains and prescribed antibiotics) in orthopaedic device-related infection management. B. Investigate the capacity of S. aureus isolates to form biofilm in presence/absence of antibiotics. C. Create an S. aureus strain collection for future ancillary studies

Conditions

• Prosthetic Joint Infection
• Staphylococcus Aureus
• Biofilm

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Antibiofilmogramme	An Antibiofilmogramme (BioFilm Control) evaluates the capacity of a series of antibiotics to inhibit the growth of bacterial biofilms for a given bacterial isolate.

Timeline

• Start date: 2015-06-01
• Primary completion: 2018-02-28
• Completion: 2021-12-01
• First posted: 2017-08-28
• Last updated: 2021-03-02

Locations

1 site across 1 country: France