NCT03251469

Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture

Single Dose of Tranexamic Acid at the Time of Surgery and Blood Loss, in Elderly Patients Undergoing Hip Fracture Surgery

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: National and Kapodistrian University of Athens · Academic / Other
• Sex: All
• Age: 75 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to investigate the hypothesis that single dose of tranexamic acid (TXA) preoperatively will lower blood loss and transfusion rate in elderly patients with hip fractures (intertrochanteric or Subcapital), that will be treated with intramedullary nailing and cemented hemiarthroplasty respectively. After application of inclusion and exclusion criteria, patients will be randomized in two groups. Group 1 will include patients that receive preoperatively single dose of TXA (15mg/kg) and Group 2 will include patients that receive normal saline (control group).

Conditions

• Blood Loss, Surgical
• Hip Fractures
• Complication, Postoperative

Interventions

Type	Name	Description
DRUG	Tranexamic Acid 15mg/kg , iv, Single Dose	Tranexamic Acid 15mg/kg , administered intravenously, preoperatively, in a single dose
DRUG	Normal Saline, 100mg, iv, Singe dose	Normal Saline, 100mg, administered intravenously, preoperatively in single dose

Timeline

• Start date: 2013-01-01
• Primary completion: 2017-12-01
• Completion: 2018-02-01
• First posted: 2017-08-16
• Last updated: 2017-08-16

Locations

1 site across 1 country: Greece