NCT03240666

Protozoans in Biofilm From Patients With Periodontitis

Multicentric Clinical Trials on the Prevalence of Entamoeba Gingivalis and Its Associated Bacterial Flora in Patients With Periodontitis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 231 (estimated)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The buccal cavity is colonized by numerous microorganisms whose the number and composition could be modified with medical background (diseases and drugs) and the level of oral hygiene of the patients. Among all microorganisms identified in the periodontium, few of them are implicated in the etiopathogenesis of periodontal pathologies. To date, four major bacteria are identified for their ability to degrade periodontal tissues. Although the periodontitis is established to be the consequence of bacterial virulence and immune dysfunction, these factors fail to explain the refractory periodontitis of some patients to etiologic treatment . Others microorganisms such as protozoans could have an impact on this disease.

Conditions

• Periodontitis, Adult

Interventions

Type	Name	Description
OTHER	non applicable	non applicable

Timeline

• Start date: 2017-04-10
• Primary completion: 2022-11-10
• Completion: 2022-11-30
• First posted: 2017-08-07
• Last updated: 2021-04-21

Locations

1 site across 1 country: France