NCT03228914

Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: The University of Texas Health Science Center, Houston · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the effects of Oxymetazoline and Epinephrine (which are 2 different nasal decongestants both of which are routinely used before sinus surgery) on blood loss and the surgeon's view of the surgical field during sinus surgery.

Conditions

• Endoscopic Sinus Surgery
• Nasal Polyps

Interventions

Type	Name	Description
DRUG	Oxymetazoline	Pledgets will be soaked in 0.05% oxymetazoline solution Two pledgets with the associated medication will be placed into the nasal cavity; one along the floor of the nose and another directed towards the middle meatus.
DRUG	Epinephrine	Pledgets will be soaked in 1:1000 epinephrine solution Two pledgets with the associated medication will be placed into the nasal cavity; one along the floor of the nose and another directed towards the middle meatus.

Timeline

• Start date: 2018-06-14
• Primary completion: 2018-08-29
• Completion: 2018-08-29
• First posted: 2017-07-25
• Last updated: 2021-01-13
• Results posted: 2021-01-13

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study