Trials / Unknown
UnknownNCT03221231
N-acetylcysteine for the Treatment of Cannabis Dependence: Working Mechanisms
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- Sponsor
- Universitair Ziekenhuis Brussel · Academic / Other
- Sex
- Male
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
This study investigates the effects of repeated NAC administration on glutamate concentrations in the anterior cingulate cortex (ACC), on neurocognitive functioning, and on neuro-inflammatory parameters in adult cannabis-dependent individuals.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | N-acetylcysteine | 1200 mg/day, twice daily, N-acetylcysteine |
| DRUG | Placebo Oral Tablet | twice daily, placebo |
| OTHER | Magnetic Resonance Imaging | |
| OTHER | Neurocognitive measures | |
| OTHER | Neuro-inflammatory measures |
Timeline
- Start date
- 2016-05-15
- Primary completion
- 2022-02-01
- Completion
- 2023-02-01
- First posted
- 2017-07-18
- Last updated
- 2020-12-08
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT03221231. Inclusion in this directory is not an endorsement.