NCT03216993

An Early Enteral Nutrition Protocol in Shanghai

The Shanghai Protocol for Early Enteral Nutrition in Mechanical Ventilated Patients

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 400 (estimated)
• Sponsor: Ruijin Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

compare different enteral nutrition strategy in patients with mechanical ventilation

Detailed description

There has been many evidence that deficiency in energy and protein take-in are associated with poor outcome in critical patients. To reach an adequate amount of energy and protein is critical in patients with respiratory failure and with mechanical ventilation, as it prevents muscle dystrophy and thus prevents ICU acquired weakness, leading to a better outcome in the end. Enteral Nutrition is preferred as it prevents gut dysfunction in respiratory failure patients, and may prevent further infection. But there are many challenge in implement a good enteral nutrition therapy, and energy or protein deficiency is common in patient with respiratory failure. There have been many protocols aiming at reaching enough enteral nutrition for ICU patients, most of which are based on a background of western and developed countries. The investigators developped a enteral nutrition protocol based on an unique cultural background of eastern developing country, trying to help the ICU patients reaching nutrition target, so that the patients may have better outcome.

Conditions

• Critical Illness
• Enteral Feeding Intolerance

Interventions

Type	Name	Description
OTHER	Standard care	Standard care: patients receive enteral nutrition in accordance with the usual practice in the participating units
OTHER	Protocol care	Protocol care： patient receive enteral nutrition in accordance with enteral nutrition protocol studied

Timeline

• Start date: 2018-12-01
• Primary completion: 2020-12-31
• Completion: 2021-10-01
• First posted: 2017-07-13
• Last updated: 2018-04-17

Locations

1 site across 1 country: China