Trials / Completed
CompletedNCT03215316
Screening Expiratory Flow Limitation by Flow-time Curve
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 45 (actual)
- Sponsor
- Unity Health Toronto · Academic / Other
- Sex
- All
- Age
- 18 Years – 99 Years
- Healthy volunteers
- Not accepted
Summary
Expiratory flow limitation (EFL) is defined as a dynamic condition that expiratory flow cannot be further increased with higher expiratory driving pressure. Under mechanical ventilation, it can cause intrinsic positive end-expiratory pressure (PEEP) and dynamic hyperinflation, and be associated with worse clinical outcome. The detection of EFL however needs special maneuvers and offline analysis of flow-volume curves, which are infeasible in routine practice and cannot be used during real-time monitoring. The investigators propose a new and simple approach using flow derived parameters to detect EFL in real time without needing any intervention.
Conditions
Timeline
- Start date
- 2017-09-01
- Primary completion
- 2024-08-12
- Completion
- 2024-08-12
- First posted
- 2017-07-12
- Last updated
- 2025-05-20
Locations
1 site across 1 country: Canada
Source: ClinicalTrials.gov record NCT03215316. Inclusion in this directory is not an endorsement.