NCT03193112

Melatonin Decreases Eye Pressure in Normotensive Patients

Melatonin Decreases Eye Pressure in Depressive Patients With Normal Intraocular Pressure

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: Kahramanmaras Sutcu Imam University · Academic / Other
• Sex: All
• Age: 18 Years – 66 Years
• Healthy volunteers: Not accepted

Summary

Agomelatine is a melatonin drug used to treat depressive disorder. Agomelatine may also some effects on ocular pressures. In this study, we aimed to demonstrate that melatonin decreases intraocular pressures when given depressive patients.

Detailed description

Melatonin has been shown to be effective to decrease intraocular pressure in experimental animal researches. Agomelatine is a melatonin derivative drug approved for the treatment of depression, which is also available in our country. Depending on animal experiments, it can be assumed that agomelatine can decrease intraocular pressure. Demonstrating that agomelatine is effective to reduce eye pressure may give a concurrent treatment of depressive patients with glaucoma. With this it may be possible to treat both diseases at the same time with single drug. In this study, the researchers intended to investigate the changes in ocular tension in normotensive depressive patients treated with agomelatine.

Conditions

• Depressive Disorder

Interventions

Type	Name	Description
DRUG	Agomelatine 25 MG Oral Tablet	We will treat our patients with Agomelatine tablet of 25 mg.

Timeline

• Start date: 2017-06-16
• Primary completion: 2017-10-15
• Completion: 2018-06-15
• First posted: 2017-06-20
• Last updated: 2018-08-13

Locations

1 site across 1 country: Turkey (Türkiye)