Trials / Active Not Recruiting
Active Not RecruitingNCT03192410
Prospective Cohort Study of 4,837 Post-myocardial Infarction Patients (Alpha Omega Cohort)
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 4,837 (actual)
- Sponsor
- Wageningen University · Academic / Other
- Sex
- All
- Age
- 60 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The Alpha Omega Cohort is a prospective study of 4,837 state-of-the-art drug-treated Dutch patients aged 60-80 years who had a clinically diagnosed myocardial infarction up to 10 years before enrolment. During the first 40 months of follow-up, patients took part in an experimental study of low doses n-3 fatty acids (Alpha Omega Trial, ClinicalTrials.gov NCT00127452). At baseline (2002-2006), data on medical history, medication use, diet, lifestyle and other factors were collected by means of questionnaires. Patients were physically examined by trained research nurses and blood samples were obtained. Follow-up for vital status and cause-specific mortality is ongoing. The trial was approved by a central medical ethics committee (Haga Hospital, The Hague, The Netherlands) and all patients provided written informed consent.
Detailed description
Details are reported in publications.
Conditions
- Cardiovascular Diseases
- Mortality
- Type 2 Diabetes Mellitus
- Cognitive Decline
- Mental Well-being
- Kidney Function
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Dietary intake | Intake of nutrients, foods, food groups, beverages; dietary patterns. |
| BEHAVIORAL | Lifestyle factors | Physical activity; smoking; alcohol use; educational level. |
| BIOLOGICAL | Blood biomarkers | Biomarkers of dietary intake (e.g. fatty acids); biomarkers of disease. |
| BIOLOGICAL | Health | Current health status; medical history; medication use; self-rated health; risk factors for disease (e.g. body mass index, blood pressure, blood lipids, glucose) |
| GENETIC | DNA | SNPs (GWAS) |
| BIOLOGICAL | Mental well-being | Cognitive function; dispositional optimism; depression. |
Timeline
- Start date
- 2002-04-01
- Primary completion
- 2040-01-01
- Completion
- 2040-01-01
- First posted
- 2017-06-20
- Last updated
- 2017-06-20
Locations
1 site across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT03192410. Inclusion in this directory is not an endorsement.