Trials / Completed
CompletedNCT03191162
Evaluation of Different Benznidazole Regimens for the Treatment of Chronic Chagas Disease.
Phase II Clinical Trial for the Evaluation of Different Benznidazole Regimens for the Treatment of Chronic Chagas Disease in Adult Patients. Berenice Project
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 238 (actual)
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
A phase 2 clinical trial to evaluate the the efficacy of different benznidazole regimens (300mg/day for 60 days, 150mg/day for 60 days, and 400mg/day for 15 days) for the treatment of chronic Chagas disease in adult patients. The efficacy is assessed through the proportion of patients with negative parasitaemia measured by Polymerase Chain Reaction (PCR) during the first 12 months after starting treatment. The study will be performed in Spain, Brazil, Argentina and Colombia.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Benznidazole | To evaluate different regimens of Benznidazole for the treatment of chronic Chagas disease |
Timeline
- Start date
- 2017-04-21
- Primary completion
- 2020-09-21
- Completion
- 2021-03-16
- First posted
- 2017-06-19
- Last updated
- 2023-12-19
Locations
7 sites across 4 countries: Argentina, Brazil, Colombia, Spain
Source: ClinicalTrials.gov record NCT03191162. Inclusion in this directory is not an endorsement.