NCT03190681

Motivation and Methylphenidate

Etude Comparative Monocentrique, Randomisée, En Cross-over, En Double Aveugle, Contre Placebo, De L'action Du Méthylphénidate Sur Les Paramètres Cognitifs De La Motivation

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: Institut National de la Santé Et de la Recherche Médicale, France · Other Government
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the impact of methylphenidate, a mixed dopaminergic and noradrenergic agent, onto the different components of motivation: decision-making, effort allocation and instrumental learning.

Conditions

• Motivation
• Apathy
• Impulsive Behavior

Interventions

Type	Name	Description
DRUG	Ritalin 10Mg Tablet	oral ingestion of 3 tablets in a single-dose
DRUG	Placebo Oral Tablet	oral ingestion of 3 tablets in a single-dose

Timeline

• Start date: 2017-07-11
• Primary completion: 2017-11-15
• Completion: 2017-11-15
• First posted: 2017-06-19
• Last updated: 2025-03-28

Locations

1 site across 1 country: France