Clinical Trials Directory

Trials / Completed

CompletedNCT03187912

Accelerated Corneal Cross-linking With Different Riboflavin Solutions

Effect-evaluation of an Accelerated Corneal Cross-linking Protocol With Different Riboflavin Solutions

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
60 (actual)
Sponsor
Medical University of Vienna · Academic / Other
Sex
All
Age
18 Years – 99 Years
Healthy volunteers
Not accepted

Summary

Following the Bunsen-Roscoe law, accelerated cross-linking protocols with higher irradiation intensities and shorter irradiation times have been introduced. In addition, new riboflavin solutions with HPMC (hydroxylpropyl methylcellulose) instead of dextran found its way into CXL-treatment. The aim of this trial is to evaluate clinical outcomes in an accelerated corneal collagen cross-linking protocol with different riboflavin solutions.

Conditions

Interventions

TypeNameDescription
DRUGRiboflavinRiboflavin with 20% Dextran or HPMC will be admininstered every 2 minutes for overall 30 minuts (Dextran) or 10 minutes (HPMC), respectively

Timeline

Start date
2016-09-19
Primary completion
2020-03-30
Completion
2020-03-30
First posted
2017-06-15
Last updated
2021-03-03

Locations

1 site across 1 country: Austria

Source: ClinicalTrials.gov record NCT03187912. Inclusion in this directory is not an endorsement.