Trials / Completed
CompletedNCT03146286
Skeletal Muscle Protein Metabolism and Insulin Sensitivity in Overweight Individuals: Effects of Meals With Various Fatty Acid Compositions
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 8 (actual)
- Sponsor
- University of Nottingham · Academic / Other
- Sex
- Male
- Age
- 40 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
The aim of the study will investigate whether impairment in the action of insulin to promote the use of glucose in skeletal muscle (insulin resistance) as a result of oral ingestion of a liquid meal rich in saturated fat is linked to reduced ability of muscles to synthesise new protein in response to dietary protein intake, which ultimately may compromise maintenance of muscle size and quality of life and whether partially replacing saturated fat in the liquid meal with omega 3 polyunsaturated FA (n3PUFA) will ameliorate these negative effects.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Saturated fat | Palm stearin |
| DIETARY_SUPPLEMENT | Placebo | Water |
| DIETARY_SUPPLEMENT | Fish Oil | Fish Oil, Omega 3 PUFA |
Timeline
- Start date
- 2015-08-01
- Primary completion
- 2015-12-03
- Completion
- 2015-12-03
- First posted
- 2017-05-09
- Last updated
- 2019-05-21
Source: ClinicalTrials.gov record NCT03146286. Inclusion in this directory is not an endorsement.