NCT03140917

Multimodal Assessment of Liver Volume and Function

Multimodal Assessment of Liver Volume and Function in Patients With Colorectal Liver Metastases

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 10 (actual)
• Sponsor: Karolinska University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In liver surgery peroperative assessment och the future liver remnant (FLR) is pivotal in order to avoid posthepatectomy liver failure. To date this is mainly performed by measuring the volume of the FLR. Of course FLR volume acts as a surrogate measure of FLR function and the correlation between volume and function is not always accurate. Several techniques to assess FLR function has been proposed. Hepatobiliary scintigraphy (HBS) and Dynamic MRI are the two such methods. In this study we compare HBS and MRI, in addition to contrast-enhanced CT and ICG, repeatedly performed before and after right hepatectomy in patients with colorectal liver metastases treated with neoadjuvant chemotherapy.

Conditions

• Colorectal Cancer
• Liver Metastases

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Multimodal liver function assessment	HBS, MRI, CE-CT and ICG

Timeline

• Start date: 2016-04-01
• Primary completion: 2019-06-01
• Completion: 2019-07-01
• First posted: 2017-05-04
• Last updated: 2019-11-26

Locations

1 site across 1 country: Sweden