NCT03140319

Transplantation of Fibroblast for Correction of Nasolabial Folds

Autologous Transplantation of Cultured Fibroblast for Correction of Nasolabial Folds

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: SCARM Institute, Tabriz, Iran · Other Government
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The study evaluated the safety and efficacy of the Autologous cultured fibroblast for correction of Nasolabial folds and inhibition of skin aging

Detailed description

Autologous cultured fibroblast which is obtain from the patient's normal skin is harvested and expanded in an in vitro. Biopsies samples are obtained from the behind of the patient's ear as a source of fibroblasts, then fibroblast cells isolated and expanded through cell culture, and used for the correction of Nasolabial folds, deep wrinkles of the forehead. Prior to final packaging, cell viability is assessed to be at least 85%

Conditions

• Nasolabial Folds
• Skin Aging

Interventions

Type	Name	Description
BIOLOGICAL	Fibroblast	Transplantation of 20 million cell by three injection
BIOLOGICAL	Placebo	Injection of Placebo

Timeline

• Start date: 2020-12-10
• Primary completion: 2021-11-15
• Completion: 2021-12-26
• First posted: 2017-05-04
• Last updated: 2020-10-27

Locations

1 site across 1 country: Iran