NCT03133182

Polypharmacy and Outcomes After Elective Noncardiac Surgery

Association of Polypharmacy With Outcomes After Elective Noncardiac Surgery: a Population-based Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 266,499 (actual)
• Sponsor: Ottawa Hospital Research Institute · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

This study investigates the association of preoperative polypharmacy with outcomes and healthcare resource utilization in a population-based sample of older patients enrolled in a universal pharmacare program

Detailed description

Multilevel multivariable regression analysis will be used to investigate the adjusted association between preoperative polypharmacy and postoperative outcomes and healthcare resource utilization. Sensitivity analyses will be used to evaluate the robustness of the primary analysis.

Conditions

• Polypharmacy
• Surgical Procedure, Operative
• Morality
• Epidemiology

Interventions

Type	Name	Description
DRUG	Polypharmacy	Patients who are taking \>=5 unique prescription drugs in the 3 months prior to surgery

Timeline

• Start date: 2002-04-01
• Primary completion: 2014-03-01
• Completion: 2014-03-01
• First posted: 2017-04-28
• Last updated: 2025-01-24
• Results posted: 2025-01-24