NCT03131492

Early Dehiscence Markers in Ovarian Cancer Surgery

Procalcitonin and C-Reactive Protein as Early Anastomotic Dehiscence Markers in Ovarian Cancer Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 92 (actual)
• Sponsor: Hospital Universitari Vall d'Hebron Research Institute · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

EDMOCS trial pretends to evaluate if C-reactive protein (CRP) and procalcitonin (PCT) can predict intestinal anastomotic leaks before early discharge in advanced ovarian cancer surgery requiring intestinal resection. These markers have already been positively tested in colorectal cancer surgery, but not yet in ovarian surgery. Patients undergoing intestinal resection in ovarian cancer surgery will be included. C-reactive protein and PCT will be measured pre-operatively, and on the second, fourth and sixth postoperative day. Thirty-day readmissions, re-operations and mortality will be recorded.

Conditions

• Ovarian Neoplasms Malignant
• Anastomotic Leak

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Blood test	C-reactive protein and PCT measured preoperatively, and on the second, fourth and sixth postoperative days.

Timeline

• Start date: 2017-03-01
• Primary completion: 2020-12-31
• Completion: 2021-07-31
• First posted: 2017-04-27
• Last updated: 2022-09-29

Locations

1 site across 1 country: Spain