Trials / Completed
CompletedNCT03131063
Pharmacokinetic Study of Antibiotics in Patients Assisted by Extracorporeal Membrane Oxygenation (PHARMECMO)
A Pilot Pharmacokinetic Study of Antibiotics in Patients Assisted by Extracorporeal Membrane Oxygenation in Intensive Care Unit
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 45 (actual)
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The PHARMECMO study is a pilot, prospective, pharmacokinetic study, conducted in a cardiac surgery intensive care unit of 18 beds. Optimization of antibiotic therapy for extracorporeal membrane oxygenation (ECMO) patients remains a pharmacological challenge. Clinical studies suggest that individualized dosing strategies and therapeutic drug monitoring could facilitate the achievement of adequate antibiotic concentration. The objective of this pilot study was to observe the pharmacokinetic characteristics of commonly used antibiotics in intensive care for patients treated with extracorporeal membrane oxygenation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Antibiotic plasma dosage | Measurement of the concentration of antibiotics administered as part of the routine care of intensive care patients |
Timeline
- Start date
- 2014-05-01
- Primary completion
- 2015-04-01
- Completion
- 2017-03-01
- First posted
- 2017-04-27
- Last updated
- 2017-04-27
Source: ClinicalTrials.gov record NCT03131063. Inclusion in this directory is not an endorsement.