NCT03130231

Predictive Value of β2-microspheres for Postoperative Delirium

The Predictive Value of β2-microspheres for Postoperative Delirium in the Elderly After Orthopedic Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 184 (actual)
• Sponsor: Zhongda Hospital · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Accepted

Summary

This study evaluated the predictive value of β2-microspheres for postoperative delirium (POD) in the elderly after orthopedic surgery. For this purpose, the levels of β2-microspheres in plasma and cerebrospinal fluid were compared between the POD and non-POD groups.

Detailed description

In this study, plasma and cerebrospinal fluid of the patients were collected to detect the levels of β2-microspheres before operation. Also, the patients were interviewed one day before the surgery and on postoperative days 1-3 by the Confusion Assessment Method and then divided them into POD and non-POD groups. The aim of the present study was to assess whether higher levels of β2-microspheres could predict the occurrence of POD.

Conditions

• Postoperative Delirium

Timeline

• Start date: 2015-10-01
• Primary completion: 2017-12-30
• Completion: 2017-12-30
• First posted: 2017-04-26
• Last updated: 2018-12-27

Locations

1 site across 1 country: China