Trials / Completed
CompletedNCT03127917
Effect of L-Citrulline on Vascular Function
Impact of Reduced Arterial Stiffness on Peripheral Vascular Function and Mobility
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 25 (actual)
- Sponsor
- Texas Tech University · Academic / Other
- Sex
- All
- Age
- 60 Years – 79 Years
- Healthy volunteers
- Accepted
Summary
The objective of this project is to determine the importance of peripheral vascular function on gait performance in older adults.
Detailed description
This project employed a placebo controlled, double-blind, crossover trial. Participants were randomized to oral L-citrulline (6 g/day) or placebo (maltodextrin) for 14 days, and switched to the other treatment for another 14 days after washout. Peripheral vascular function was assessed under conditions of rest, leg exercise, and cognitive engagement. Gait performance was assessed using clinical walking tests.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | L-citrulline | L-citrulline capsules given at 6 g/day |
| OTHER | Placebo | Maltodextrin capsules given as placebo |
Timeline
- Start date
- 2015-07-01
- Primary completion
- 2017-03-22
- Completion
- 2017-12-31
- First posted
- 2017-04-25
- Last updated
- 2018-05-04
Source: ClinicalTrials.gov record NCT03127917. Inclusion in this directory is not an endorsement.