Trials / Completed
CompletedNCT03122977
Acute-phase Response & Periodontal Treatment in Obese Patients
Acute-phase Response Following Full-mouth Versus Quadrant Non-surgical Periodontal Treatment in Obese Subjects: A Randomized Clinical Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 38 (actual)
- Sponsor
- University of Pisa · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study is to compare quadrant scaling and root planing (Q-SRP) versus full-mouth treatment (FM-SRP) in terms of acute-phase responses following no surgical periodontal treatment in obese patients affected by periodontitis.
Detailed description
Periodontal treatment, consisting in both supra- and sub-gingival mechanical instrumentation of the root surface (scaling and root planing), will be performed by a single periodontist on obese patients with periodontitis. The aim of this study is to compare quadrant scaling and root planing (Q-SRP) versus full-mouth treatment (FM-SRP) in terms of acute-phase responses following non surgical periodontal treatment. Treatment will be provided using both hand and ultrasonic instrumentation with fine tips. FM-SRP patients will received treatment within 24 h. Q-SRP patients will received four quadrants sessions of periodontal treatment with an interval of 1 week between sessions. Vital, endothelial function and blood inflammatory parameters will be evaluated at baseline, 24 hours after the first treatment and after 3 months. Periodontal parameters will be evaluated at baseline and after 3 months.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | FM-SRP | Supra- and sub-gingival mechanical instrumentation of the root surface of the whole dentition within 24 hours. |
| PROCEDURE | Q-SRP | Supra- and sub-gingival mechanical instrumentation of the root surface will be performed in all dentition subdivided in four appointments. Each appointment will be performed in one week interval. In each appointment only a "quadrant" of the dentition will be instrumented. |
Timeline
- Start date
- 2016-06-01
- Primary completion
- 2020-06-01
- Completion
- 2021-10-01
- First posted
- 2017-04-21
- Last updated
- 2022-11-03
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT03122977. Inclusion in this directory is not an endorsement.