NCT03117231

Effects of tDCS in Elderly With Pain Due to Knee Osteoarthritis

Effects of Transcranial Direct Current Stimulation (tDCS) on Knee Osteoarthritis Pain in Elderly Subjects With Defective Endogenous Pain-Inhibitory System: Protocol for a Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 104 (actual)
• Sponsor: Federal University of São Paulo · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate if anodal tDCS stimulation over M1 may decrease chronic knee OA pain in elderly subjects with defective CPM. In addition, this trial will help to investigate the role of central sensitization in knee OA and evaluate how tDCS stimulation may affect it.

Conditions

• Osteoarthritis, Knee
• Chronic Pain

Interventions

Type	Name	Description
DEVICE	Active Transcranial Direct Current Stimulation (tDCS)	Subjects will undergo 15 sessions of tDCS stimulation, 1x per day at 20 minutes per session, of up to 2mA. During active stimulation, the current will be active for the full 20 minutes.
DEVICE	Sham Transcranial Direct Current Stimulation (tDCS)	Subjects will undergo 15 sessions of tDCS stimulation, 1x per day at 20 minutes per session, of up to 2mA. However, during sham stimulation (placebo) the current will not be active for the full 20 minutes

Timeline

• Start date: 2018-03-15
• Primary completion: 2019-06-01
• Completion: 2019-07-01
• First posted: 2017-04-17
• Last updated: 2019-09-09

Locations

1 site across 1 country: Brazil