NCT03114397

Long-term Effect of tDCS in Patients With Disorders of Consciousness

Long-term Effect of 20 Sessions of Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness: a Double Blind Sham Controlled Clinical Trial.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 62 (actual)
• Sponsor: University of Liege · Academic / Other
• Sex: All
• Age: 16 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

In this multicentric double-blind sham controlled study, the investigators plan to assess the effects of 20 sessions of tDCS on long-term behavioral recovery in patients with disorders of consciousness. Neurophysiological outcomes (EEG) will also be collected. This research will 1) determine whether long-term behavioral recovery can be promoted with tDCS and 2) generate knowledge regarding the impact of tDCS on neurophysiological outcome (i.e., EEG) in severely brain injured patients. The investigators will compare the effects of active and sham tDCS on behavioral assessments and quantitative EEG in patients with severe brain injury and its potential application in rehabilitation.

Conditions

• Disorder of Consciousness

Interventions

Type	Name	Description
DEVICE	transcranial direct current stimulation - active	transcranial direct current stimulation will be applied over the left dorsolateral at 2 mA for 20minutes.
DEVICE	transcranial direct current stimulation - sham	transcranial direct current stimulation will be applied over the left dorsolateral at 2 mA for 20minutes. The sham intervention consists of 30 seconds of stimulation at the beginning and the end of the 20minutes of intervention.

Timeline

• Start date: 2017-09-01
• Primary completion: 2021-12-24
• Completion: 2021-12-24
• First posted: 2017-04-14
• Last updated: 2022-11-03

Locations

1 site across 1 country: Belgium