NCT03111719

Human Brown Adipose Tissue and Mitochondrial Respiration

Human Brown Adipose Tissue Histological and Mitochondrial Respiratory Analysis

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 180 (estimated)
• Sponsor: Maastricht University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study is focused on measuring mitochondrial activity of human brown adipose tissue. During surgery, adipose tissue biopsies from white and brown adipose tissue will be collected from the deep neck area. These biopsies will be used to examine mitochondrial function via histological analysis, biochemical analysis and in vitro experiments based on precursor cells present in the biopsies.

Conditions

• Mitochondrial Metabolism Disorders
• Adipose Tissue, Brown
• Aging
• Obesity

Timeline

• Start date: 2010-01-04
• Primary completion: 2021-10-10
• Completion: 2021-10-10
• First posted: 2017-04-13
• Last updated: 2020-02-21

Locations

1 site across 1 country: Netherlands