NCT03107650

Preoperative Prediction Model of Pathological Outcomes (Mesorectum Quality and Positive Circumferential Resection Margin) in Patients With Mid-low Rectal Cancer

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 323 (actual)
• Sponsor: Pere Planellas Giné · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Elaboration of a preoperative prediction model of the quality of the mesorectum and the involvement of the circumferential margin in patients with mid-low rectal cancer who undergo laparoscopic anterior rectal resection. In a second phase the investigators will study the utility of the prediction model in classifying patients with high risk of suboptimal quality of mesorectum and/or positive circumferential margin. Patients with high preoperative risk will undergo a transanal total mesorectal excision and patients with low risk a laparoscopic transabdominal mesorectal excision. The investigators finally will compare pathological outcomes ( quality of mesorectum and circumferential margin), survival and recurrence between the two groups.

Conditions

• Rectal Cancer

Interventions

Type	Name	Description
PROCEDURE	Transanal total mesorectal excision of rectal cancer	To perform a total mesorectal excision through a transanal approach

Timeline

• Start date: 2018-01-01
• Primary completion: 2019-07-31
• Completion: 2020-07-31
• First posted: 2017-04-11
• Last updated: 2021-09-05

Locations

1 site across 1 country: Spain