NCT03104946

To Research the Relation Between Neonatal Morbidities and Poor Outcome in Preterm Infants

Clinical Research on the Predictive Effect of Neonatal Morbidities on the Poor Outcomes to Very Low Birth-weight and Extremely Low Birth-weight Infants

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 834 (actual)
• Sponsor: yangjie · Academic / Other
• Sex: All
• Age: 1 Month – 12 Months
• Healthy volunteers: Not accepted

Summary

From November 2014 to October 2015, a multi-centers retrospective study was conducted to collect compliance, and 8 three-level hospitals from China were included. The infants survived to a postmenstrual age of 36 week with birth weight less than 1500g and without congenital disease. The birth weight, gestational age, morbidities and poor outcomes( death, cerebral palsy, cognitive, et al) were recorded. Data were analyzed with Chi-square test to observe the relationship between morbidities and poor outcomes. And the predictive effect on the number of the top three morbidities were analyzed by Logistic regression analysis.

Conditions

• Preterm Infant
• Morbidity;Infant
• Outcome, Fatal

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Mental Development Index;Auditory Brainstem Response;okineticnystagmus	mental development index(MDI）\<70:cognitive delay do not pass auditory brainstem response(ABR）：hearing impairment do not pass okineticnystagmus:visual impairment Patent Ductus Arteriosus

Timeline

• Start date: 2013-09-01
• Primary completion: 2015-11-30
• Completion: 2016-11-30
• First posted: 2017-04-07
• Last updated: 2017-04-07