NCT03095729

Cognitive Consequences of an Activation of the Cortical Drive to Breath (VENTIPSY)

Cognitive Consequences of an Activation of the Cortical Drive to Breath

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 65 (actual)
• Sponsor: Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of the study is to measure the negative cognitive consequences of the ventilation under pathological or experimental cortical drive to breath.

Detailed description

Cognitive capacities are measured on healthy subject submitted to inspiratory threshold loading, patients treated by chronic mechanical ventilation due to suffering Ondine syndrome or amyotrophic lateral sclerosis. The spontaneous breathing is compared to NIV breathing or inspiratory threshold loading.

Conditions

• Ondine Syndrome
• Healthy
• Amyotrophic Lateral Sclerosis

Interventions

Type	Name	Description
OTHER	Neuropsychological tests	A battery of tests to evaluate the overall cognitive performance of the subjects (memory, executive, attentional or instrumental functions)

Timeline

• Start date: 2017-04-26
• Primary completion: 2019-07-04
• Completion: 2019-07-04
• First posted: 2017-03-30
• Last updated: 2021-07-09

Locations

1 site across 1 country: France