Trials / Unknown
UnknownNCT03076580
An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China
An Integrative-omics Study to Identify New Biomarkers of Cardiomyopathy Patients in China
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 2,000 (estimated)
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
This is a multi-omics research of Chinese cardiomyopathies patients, aiming to determine genetic risk factor and serial biomarkers of cardiomyopathies in diagnosis and prognosis.
Detailed description
Identification of novel biomarkers is needed to improve the diagnosis and prognosis of cardiomyopathy. Also,the marked variation of genes which is still unclear, may influence clinical outcomes is determined in part by genetic heterogeneity of the systemic response to pathological process. Specific aim: 1. Proteomics, microRNA-seq and metabolomics will be to determine the correlation of echocardiographic parameters of systolic and diastolic functional entry with circulating molecules 2. Genomics will be to determine the association of clinical outcome
Conditions
- Dilated Cardiomyopathy
- Hypertrophic Cardiomyopathy
- Arrhythmogenic Right Ventricular Cardiomyopathy
- Left Ventricular Non-compaction
- Restrictive Cardiomyopathy
Timeline
- Start date
- 2015-07-01
- Primary completion
- 2018-07-01
- Completion
- 2021-12-31
- First posted
- 2017-03-10
- Last updated
- 2018-04-19
Locations
3 sites across 1 country: China
Source: ClinicalTrials.gov record NCT03076580. Inclusion in this directory is not an endorsement.