Clinical Trials Directory

Trials / Completed

CompletedNCT03068312

A Study to Evaluate Efficacy of Ivacaftor in Subjects With Cystic Fibrosis Who Have a 3849 + 10KB C→T or D1152H CFTR Mutation

A Randomized, Double-blind, Placebo-controlled, Crossover Study to Evaluate the Efficacy of Ivacaftor in Subjects With Cystic Fibrosis Who Are 6 Years of Age and Older and Have Either a 3849 + 10KB C→T or D1152H-CFTR Mutation

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
38 (actual)
Sponsor
Vertex Pharmaceuticals Incorporated · Industry
Sex
All
Age
6 Years
Healthy volunteers
Not accepted

Summary

This study will evaluate the efficacy of ivacaftor treatment in subjects with CF 6 years of age and older who have a 3849 + 10KB C→T or D1152H CFTR mutation.

Conditions

Interventions

TypeNameDescription
DRUGIvacaftorIVA 150 mg tablet.
DRUGPlaceboPlacebo matched to IVA tablet.

Timeline

Start date
2017-07-18
Primary completion
2018-12-18
Completion
2018-12-18
First posted
2017-03-01
Last updated
2020-02-26
Results posted
2020-01-06

Locations

1 site across 1 country: Israel

Regulatory

Source: ClinicalTrials.gov record NCT03068312. Inclusion in this directory is not an endorsement.