NCT03049059

A Comparative Study for Efficacy and Safety Between 4% Hydroquinone Cream With or Without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Mae Fah Luang University Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

A Comparative study for Efficacy and Safety Between 4% hydroquinone cream with or without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type Melasma

Detailed description

Primary Objective: * To compare clinical efficacy by Modified MASI score between Fractional Picosecond 1,064 nm laser and daily application of 4% hydroquinone with 4% hydroquinone alone Secondary objectives * To compare the clinical endpoints of Mexameter Melanin Index, brownish spot and Ultraviolet spots by VISIATM complexion analysis, The Antera 3D® imaging technology for pigmentation, quality of life by Dermatology Life Quality Index and patient's satisfaction between Fractional Picosecond 1,064 nm laser and 4% hydroquinone with 4% hydroquinone alone

Conditions

• Picoseconds Laser
• Melasma

Interventions

Type	Name	Description
DEVICE	Fractional Picosecond 1,064 nm laser	Fractional Picosecond 1,064 nm laser and daily application with 4% hydroquinone cream
DRUG	4% hydroquinone cream

Timeline

• Start date: 2016-06-01
• Primary completion: 2016-12-01
• Completion: 2017-02-01
• First posted: 2017-02-09
• Last updated: 2017-02-09