NCT03044405

Focused Assessed Echocardiography to Predict Fluid Responsiveness

Focused Assessed Echocardiography to Predict Fluid Responsiveness for Non-cardiac Hypotensive Spontaneously Breathing Patients After Major Abdominal Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Lithuanian University of Health Sciences · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aims of the study are: 1. To evaluate the feasibility of echocardiography monitoring in postoperative unit; 2. To assess diagnostic value of different focussed echocardiography parameters to define fluid responsiveness for non-cardiac hypotensive spontaneously breathing patients after major abdominal surgery.

Detailed description

As there are different strategies of perioperative fluid management discussion which is the choice liberal or restrictive one occurs? Individualized infusion therapy should be the goal. The investigators hypothesize extended hemodynamic monitoring based on focused transthoracic echocardiography enable to differentiate the cause of hypotension more carefully and fluid overload will be avoided after major abdominal surgery. The goals of the study are: * To conduct one group of hypotensive patients after major abdominal surgery. To divide this group into responders and nonresponders after fluid challenge. * To evaluate the feasibility of echocardiography monitoring in postoperative unit (having in mind such restrains as supine position, postoperative pain, bandages etc.) * To compare the evaluation of fluid responsiveness by clinical signs and focused assessed echocardiography data. * To identify the best focused echocardiography parameters for prognosis of fluid responsiveness. * To determine if extended hemodynamic monitoring changes postoperative fluid management.

Conditions

• Hypovolemia
• Surgery
• Hypotension

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Fluid challenge	Fluid bolus of 500 ml of crystalloids is given over 15 minutes. Positive fluid responsiveness is defined by an increase in SV of at least 15%.
DIAGNOSTIC_TEST	Focused transthoracic echocardiography	Focused transthoracic echocardiography is performed to assess expansion of stroke volume after fluid challenge. Also mitral E and A waves, left ventricle outflow tract velocity time integral (LVOT VTI) and its variability, inferior vena cava diameters during breathing cycles are measured.

Timeline

• Start date: 2016-05-01
• Primary completion: 2016-08-23
• Completion: 2016-09-01
• First posted: 2017-02-07
• Last updated: 2017-02-07