NCT03044041

Comparison Between Low Dose and High Dose Intra-articular Tranexamic Acid in Total Knee Arthroplasty

Topical Intra-Articular High Doses Compared With Low Doses of Tranexamic Acid to Reduce Blood Loss in Primary Total Knee Arthroplasty: A Double-Blind Randomized Controlled Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Thammasat University · Academic / Other
• Sex: All
• Age: 50 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare blood loss between using low dose (500 mg) and high dose (3 g) topical intra-articular tranexamic acid after total knee arthroplasty in double-blind RCT

Conditions

• Blood Loss, Surgical

Interventions

Type	Name	Description
DRUG	Tranexamic Acid	IA (intra-articular) tranexamic acid after capsule closure

Timeline

• Start date: 2016-01-01
• Primary completion: 2017-01-01
• Completion: 2017-06-01
• First posted: 2017-02-06
• Last updated: 2018-01-30

Locations

1 site across 1 country: Thailand