Trials / Terminated
TerminatedNCT03020797
A Clinical Trial to Evaluate the Safety and Efficacy of Fycompa in Subjects With Amyotrophic Lateral Sclerosis (ALS)
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Stony Brook University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This is a pilot trial to test perampanel (Fycompa; Eisai, Inc.) in ALS patients. The investigators will focus on safety and preliminary signs of efficacy. Perampanel is approved by the FDA for treatment of seizures in patients with epilepsy. In this study, perampanel will be used off-label for adults with ALS at an oral medication dose on the low end of the recommended dose range for epilepsy. This study will consist of two treatments arms: perampanel and matching placebo randomized at a 1:1 ratio. Subjects will receive medication for 9 months.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Perampanel | |
| DRUG | Placebo Oral Tablet |
Timeline
- Start date
- 2017-01-12
- Primary completion
- 2023-01-31
- Completion
- 2023-02-08
- First posted
- 2017-01-13
- Last updated
- 2023-05-06
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03020797. Inclusion in this directory is not an endorsement.