Trials / Unknown
UnknownNCT03017625
Platelet Activation and Reactivity in Acute Exacerbations of COPD
Platelet Activation and Responsiveness in Patients With Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AE-COPD)
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 30 (estimated)
- Sponsor
- Radboud University Medical Center · Academic / Other
- Sex
- All
- Age
- 40 Years – 99 Years
- Healthy volunteers
- Not accepted
Summary
Chronic obstructive pulmonary disease (COPD) is known for development of severe cardiovascular co-morbidities. Systemic inflammation during acute exacerbations of COPD (AE-COPD) is thought to play a role in development of cardiovascular disease. Platelets contribute to acute cardiovascular events and atherosclerosis. When platelets are activated, they form complexes with monocytes. These platelet-monocyte complexes (PMCs) are an early process in atherothrombosis and promote inflammation. In COPD, platelet function in AE-COPD is scarcely studied. This study aims to address this gap by investigating platelet function and coagulation in patients with AE-COPD and after convalescence.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Blood is drawn | Blood analyses |
Timeline
- Start date
- 2017-01-01
- Primary completion
- 2017-06-01
- Completion
- 2017-09-01
- First posted
- 2017-01-11
- Last updated
- 2017-01-11
Source: ClinicalTrials.gov record NCT03017625. Inclusion in this directory is not an endorsement.