NCT03004430

Mantra Meditation in Major Depression

Mantra Meditation as Adjunctive Therapy in Major Depression: a Randomized Controlled Trial

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 123 (actual)
• Sponsor: Diakonie Kliniken Zschadraß · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To evaluate effects of mantra meditation on depressive symptoms if applied as adjunctive therapy to psychotherapy and/or antidepressant drugs and to explore if meditation leads to increased spirituality as a potential mediating factor of positive mental health.

Detailed description

Primary objective To measure the difference in efficacy between treatment as usual (TAU) + Mantra meditation (MAM) 20min per day and TAU + progressive muscle relaxation (PMR) 20min per day in the treatment of depressive symptoms in patients with Major Depression after inpatient treatment, after 3 months and after 6 months of treatment as assessed by the Montgomery-Åsberg Depression Rating Scale (MADRS). Secondary objectives (exploratory) 1. Differences between and within groups in self-rated depression, rumination, automatic negative thinking or trait-anxiety. 2. Differences between and within groups in measures of spirituality. 3. Correlation between measures of spirituality and change of psychometric scores. 4. Change in stress response and relaxation response after inpatient treatment, compared to baseline. 5. Difference in adherence and depth of practice between groups and within groups and correlation to psychometric outcomes.

Conditions

• Depression

Interventions

Type	Name	Description
BEHAVIORAL	Mantra Meditation	Silent mantra meditation with spiritual mantra
BEHAVIORAL	Progressive Muscle Relaxation	Progressive Muscle Relaxation

Timeline

• Start date: 2017-01-12
• Primary completion: 2020-07-30
• Completion: 2020-07-30
• First posted: 2016-12-28
• Last updated: 2021-02-03

Locations

1 site across 1 country: Germany