NCT02970721

Use of Psychotropic Medications Among Pregnant Women With Bipolar Disorder

Use of Psychotropic Medications Among Pregnant Women With Bipolar Disorder: Patterns, Determinants, and Impact on Perinatal Outcomes

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,357 (actual)
• Sponsor: Western University, Canada · Academic / Other
• Sex: Female
• Age: 15 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The objectives of the proposed project are: 1. To describe the patterns of mood stabilizer, antipsychotic, antidepressant, and anxiolytic prescriptions during pregnancy over a period of 12 years (2002-2014) in women aged 13 to 50 years who are diagnosed with bipolar disorder in Ontario. 2. To identify the factors associated with use of antipsychotics, antidepressants, and antipsychotic-antidepressant polytherapy in pregnant women diagnosed with bipolar disorder. 3. To assess the impact of antipsychotics, antidepressants, and antipsychotic-antidepressant polytherapy on the risk of maternal, neonatal, and labour and delivery outcomes in women with bipolar disorder. 4. To assess the impact of antipsychotics, antidepressants, antipsychotic-antidepressant polytherapy on psychiatric readmission rates during the early postpartum period in women with bipolar disorder.

Conditions

• Bipolar Disorder
• Pregnancy Complications

Interventions

Type	Name	Description
DRUG	Antipsychotic	Antipsychotic monotherapy
DRUG	Antidepressant	Antidepressant monotherapy
DRUG	Antipsychotic and Antidepressant	Polytherapy

Timeline

• Start date: 2016-09-01
• Primary completion: 2018-05-01
• Completion: 2018-05-01
• First posted: 2016-11-22
• Last updated: 2018-05-11