NCT02964611

Social Cognition and Personality Changes in Alzheimer's & Parkinson's Disease & Frontotemporal Lobar Degeneration

Assessing Changes in Social Cognition and Personality in Patients with Frontotemporal Lobar Degeneration, Alzheimer's Disease and Parkinson's Disease and Their Effect on the Patient-caregiver Relationship

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 120 (estimated)
• Sponsor: University Health Network, Toronto · Academic / Other
• Sex: All
• Age: 50 Years – 90 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to compare personality and social cognition changes, including emotion detection and self-awareness, and neuroanatomical correlates in patients, and how that affects the caregiver-patient relationship.

Detailed description

The purpose of this study is to understand social cognition changes in patients with Alzheimer's disease (AD), Parkinson's disease (PD), and Frontotemporal Lobar Degeneration (FTLD), which includes Progressive Supranuclear Palsy (PSP), Corticobasal Syndrome (CBS) and Frontotemporal Dementia (FTD - behavioural variant frontotemporal dementia, progressive non-fluent aphasia and semantic dementia), and the effect of these changes on the patients' relationship with their caregivers. In addition, the study aims to provide a greater clarity in the neuroanatomical correlates of social cognition in patients with FTLD, PD and AD.

Conditions

• Alzheimer's Disease
• Parkinson's Disease
• Frontotemporal Lobar Degeneration

Interventions

Type	Name	Description
BEHAVIORAL	Observational Study	This is an observational study.

Timeline

• Start date: 2013-01-01
• Primary completion: 2016-08-16
• Completion: 2016-08-16
• First posted: 2016-11-16
• Last updated: 2024-12-18

Locations

1 site across 1 country: Canada