NCT02958046

The Efficacy of Lansoprazole and Domperidone Combination on Intragastric and Intraesophageal Acidity

Phase 4 Study, Assessing the Efficacy of Lansoprazole and Domperidone Combination on Intragastric and Intraesophageal Acidity

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Neutec Ar-Ge San ve Tic A.Ş · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the efficacy of lansoprazole combination with domperidone on intragastric acidity and intraesophageal acidity, GERD symptoms, impedance kinetics, gastric emptying in patients with gastroesophageal reflux disease (GERD).

Detailed description

Objectives of the trial to assess the efficacy of lansoprazole in combination with domperidone on gastric acidity, intraesophageal acidity, GERD symptoms, impedance kinetics and gastric emptying in patients with GERD. 24 hour pH measurement and gastric emptying test will be done at screening visit and after 7 days of drug treatment. Twelve patients will take one tablet for 7 days.

Conditions

• Gastroesophageal Reflux Disease

Interventions

Type	Name	Description
DRUG	Lansoprazole/Domperidone	DUOLANS 30/30 mg SR tablet per oral, one tablet daily

Timeline

• Start date: 2014-01-01
• Primary completion: 2015-05-01
• Completion: 2015-08-01
• First posted: 2016-11-08
• Last updated: 2016-11-08

Locations

1 site across 1 country: Turkey (Türkiye)