Trials / Completed
CompletedNCT02948660
A Promising Tool for Predicting Consciousness Evolution in Prolonged Disorders of Consciousness
EEG Dynamics Induced by Zolpidem Forecasts Consciousness Evolution in Prolonged Disorders of Consciousness and Quantification of EEG Reactivity Predicts Recovery of Consciousness
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 36 (actual)
- Sponsor
- Xijing Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The research contains two parts. Part 1: To explore whether EEG responses to zolpidem can assess consciousness circuit integrity and predict the evolution of consciousness in patients with prolonged disorders of consciousness; Part 2: To explore if quantitative EEG reactivity might predict the prognosis of disorders of consciousness.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Zolpidem Tartrate Tablets | All participants were administered 10 mg of zolpidem tartrate tablets either via a feeding tube (for patients with prolonged disorders of consciousness) or orally. |
Timeline
- Start date
- 2017-12-01
- Primary completion
- 2019-06-30
- Completion
- 2019-06-30
- First posted
- 2016-10-28
- Last updated
- 2022-05-31
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT02948660. Inclusion in this directory is not an endorsement.