NCT02941874

Determining of Normal Values and Conformity Assessment of the Dosage of a Plasmatic Marker of the Cellular Captation of Glucose: the IRAP Protein

Determining of Normal Values and Conformity Assessment of the Dosage of a Plasmatic Specific Marker of the Cellular Captation of Glucose: the IRAP Protein (Insulin Regulated AminoPeptidase)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 96 (actual)
• Sponsor: University Hospital, Grenoble · Academic / Other
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is on one hand to verify the measurement conformity of the IRAP dosage and on the other hand to obtain normal values of the blood IRAP concentration on healthy volunteers.

Detailed description

This study consists of two visits, from two to five days apart. The first visit : * Healthy volunteers will be on an empty stomach. * they will have a clinical examination, blood tests and blood samples will be taken to constitute a blood collection. the IRAP concentration will be measured with those samples. The second visit : This visit will take place in an interval from 2 to 5 days after the first visit. * Subjects will be on an empty stomach * An oral glucose tolerance test (OGTT) of 3 hours will be performed. Blood samples will be taken three time 15 minutes apart at Baseline (before taking the glucose). And then after the glucose intake, blood sample will be taken every 15 minutes to measure insulinemia, blood glucose, and IRAP concentration.

Conditions

• Insulin Resistance

Interventions

Type	Name	Description
OTHER	Blood sample collection during an OGTT to assess IRAP blood concentration	Blood sample collection during an OGTT to assess IRAP blood concentration. Blood samples will be collected every 15 minutes during 3 hours

Timeline

• Start date: 2017-04-07
• Primary completion: 2019-09-16
• Completion: 2019-12-12
• First posted: 2016-10-21
• Last updated: 2020-11-04

Locations

1 site across 1 country: France