NCT02934724

Impact of HPV Vaccine On The Prevalence Of HPV In Norway

Impact of HPV Vaccine On The Prevalence Of Human Papillomavirus In Mouth And Vagina In Norway

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 315 (actual)
• Sponsor: Oslo University Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 20 Years
• Healthy volunteers: Accepted

Summary

The overall aim of the study is to assess the effect of school-based Human Papillomavirus (HPV) vaccination by comparing type-specific HPV prevalence between vaccinated and non-vaccinated women born in 1997. Women born in 1997, residence to Norway in 2009 (the year of vaccine initiation of the 1997-cohort) are invited to participate in the study.

Detailed description

This cohort is amongst the first that was offered HPV vaccine in an organized vaccination programme globally. The women will be recruited through Facebook ads. The study will enable us to measure differences in the prevalence of HPV types in vagina and the mouth between vaccinated and non-vaccinated young women in Norway. The womens vaccination status will be validated by linkage to the Norwegian Immunisation Registry (SYSVAK) and their residence status will be validated through linkage to the Norwegian Population Registry.

Conditions

• Cervical Intraepithelial Neoplasia
• Cervical Cancer
• Oropharyngeal Cancer

Interventions

Type	Name	Description
PROCEDURE	Self sample from vagina	Self sample using The Rover's Evalyn Brush
PROCEDURE	Self sample from the oral cavity	Self sample using COPAN FloqSwab
OTHER	Questionnaire	Questionnaire about vaccination status and sexual behaviour

Timeline

• Start date: 2016-11-01
• Primary completion: 2017-02-01
• Completion: 2017-02-01
• First posted: 2016-10-17
• Last updated: 2020-12-14

Locations

1 site across 1 country: Norway