Trials / Completed
CompletedNCT02915601
Bicarbonate Administration in CKD
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 109 (actual)
- Sponsor
- University of Colorado, Denver · Academic / Other
- Sex
- All
- Age
- 21 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
Low serum bicarbonate levels, even within the normal laboratory range, are strongly associated with increased risks of hypertension, endothelial dysfunction, cardiovascular disease and death. The current proposal will investigate whether bicarbonate administration in patients with chronic kidney disease (CKD) will improve the health and function of arteries and reduce the size of the left ventricle of the heart. Overall, the proposed research will provide important new scientific evidence upon which physicians can base recommendations to patients with CKD to decrease the risk of developing cardiovascular diseases.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Sodium bicarbonate | |
| DRUG | Placebo |
Timeline
- Start date
- 2017-01-15
- Primary completion
- 2022-05-19
- Completion
- 2022-05-19
- First posted
- 2016-09-27
- Last updated
- 2023-07-25
- Results posted
- 2023-07-25
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02915601. Inclusion in this directory is not an endorsement.