NCT02890888

Effect of Hyperbaric Oxygen on Functional Connectivity in Patients With Cerebral Small Vessel Disease

The Effect of Hyperbaric Oxygen on the Functional Connectivity of Resting State Neural Networks in Patients With Cerebral Small Vessel Disease

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (actual)
• Sponsor: St. Luke's Hospital, Chesterfield, Missouri · Academic / Other
• Sex: All
• Age: 50 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Patients will have a Functional MRI before and after 10 hyperbaric Oxygen treatments.

Detailed description

Functional MRI studies will be done before and 4-6 weeks after Hyperbaric Oxygen treatment to assess changes in connectivity of resting state neural networks. 10 hyperbaric treatments at 2 atmospheres absolute for 1 hour at pressure will be administered. A review of symptoms and and thorough clinical neurological examination by an experienced neurologist familiar with these studies will be done before and 4-6 weeks after the hyperbaric treatments.

Conditions

• Cerebral Small Vessel Diseases

Interventions

Type	Name	Description
OTHER	hyperbaric oxygen treatment	Patients are treated in a hyperbaric oxygen chamber for 1 hour at 2ATA, 10 times over 2 consecutive weeks, 5 times per week

Timeline

• Start date: 2014-11-01
• Primary completion: 2017-10-25
• Completion: 2017-10-25
• First posted: 2016-09-07
• Last updated: 2017-10-27

Locations

3 sites across 1 country: United States