NCT02886650

Impact of Thermocoagulation During Invasive EEG Monitoring in Children With Focal Drug-resistant Epilepsies

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Fondation Ophtalmologique Adolphe de Rothschild · Network
• Sex: All
• Age: 18 Months – 17 Years
• Healthy volunteers: Not accepted

Summary

When focal epilepsies become drug-resistant, it could be eligible for cortical surgical resection. Therefore, an invasive EEG monitoring with depth electrodes is often needed during presurgical evaluation. Some of these children can have access to thermocoagulation inside the ictal onset zone, at the end of the monitoring and before to remove the electrodes. These thermocoagulations can disorganize the epileptogenic network thanks to millimetric cortical lesions around the electrodes. The aim is to stop or at least, to reduce the seizure frequency for few weeks or months. This could be a benefit for the child, and also a confirmation of the ictal onset zone and guide the surgeon. This technique is currently used in adult population for years, but remains very rare in children.

Conditions

• Epilepsy

Interventions

Type	Name	Description
PROCEDURE	Thermocoagulation	Thermocoagulation During pre-surgical Invasive EEG Monitoring

Timeline

• Start date: 2015-12-01
• Primary completion: 2023-03-28
• Completion: 2024-05-28
• First posted: 2016-09-01
• Last updated: 2026-04-15

Locations

1 site across 1 country: France