NCT02876757

5 Alpha Reductase Inhibitors And The Risk Of Suicide And Depression

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 186,394 (actual)
• Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Academic / Other
• Sex: Male
• Age: 66 Years – 120 Years
• Healthy volunteers: Not accepted

Summary

In December 2015, Health Canada issued a warning about a potential relationship between suicide and finasteride use and called for further research. No population based studies have assessed the risk of suicide with finasteride use, and this risk is not currently part of the product monograph. Furthermore, the link between depression and finasteride has not been well studied in the older population who are the primary users of this medication.

Conditions

• BPH
• Depression
• Suicide

Interventions

Type	Name	Description
DRUG	5ARI	Exposure to finasteride/dutasteride

Timeline

• Start date: 2003-01-01
• Primary completion: 2013-12-01
• Completion: 2017-03-01
• First posted: 2016-08-24
• Last updated: 2024-01-12
• Results posted: 2018-02-05