NCT02858960

High Flow Nasal Cannula and Exercise in Chronic Obstructive Pulmonary Disease (COPD)

Comparing Exercise Capacity in Patients With COPD Using High Flow Nasal Cannula Oxygen vs The Venturi Mask

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Hospital Italiano de Buenos Aires · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare exercise capacity in COPD patients through two different systems of supplemental oxygen delivery: High Flow Nasal Cannula Oxygen (HFNCO) and The Venturi Mask (VM).

Detailed description

Design: interventional, crossover, randomized. The main goal of this study is to compare the maximum speed reached in an Incremental Load Treadmill Test (ILTT) and max time tolerated in a Constant Treadmill Load Test (CTLT) while using two different oxygen delivery devices (High Flow Nasal Cannula Oxygen and The Mask Venturi). Patients will be evaluated through two different kinds of tests: Incremental Load Treadmill Test (ILTT) and Constant Treadmill Load Test (CTLT). Each test will be conducted two times, once using HFNCO and the other time with The VM. In total, each patient will be evaluated four times on four different visits. The testing order will be randomized through STATA. The following variables will be measured before, during and after each test: 1. Max speed reached in an Incremental load test: Km/h 2. Max time tolerate in a Constant Load Test: in seconds 3. Oxygen saturation: % 4. Dyspnea: Modified Borg scale (0-10) 5. Cardiac rate: beats per minute 6. Respiratory rate: breaths per minute 7. Blood pressure: mmHg 8. Lower limbs fatigue: modified Borg scale (0-10) 9. Global comfort according to the device used: visual analogue scale (VAS) 0-10

Conditions

• COPD

Interventions

Type	Name	Description
DEVICE	High Flow Nasal Cannula Oxygen	Exercise capacity testing according to High Flow Nasal Cannula Oxygen in COPD patients involved in a Pulmonary Rehabilitation program.
DEVICE	The Venturi Mask	Exercise capacity testing according to the oxygen Mask Venturi in COPD patients involved in a Pulmonary Rehabilitation program.

Timeline

• Start date: 2016-04-01
• Primary completion: 2017-04-30
• Completion: 2017-04-30
• First posted: 2016-08-08
• Last updated: 2017-05-09

Locations

1 site across 1 country: Argentina