Trials / Completed
CompletedNCT02851173
Cognitive Enhancement Through Transcranial Laser Therapy
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 91 (actual)
- Sponsor
- University of Texas at Austin · Academic / Other
- Sex
- All
- Age
- 45 Years
- Healthy volunteers
- Accepted
Summary
This is a mechanism-driven translational project to test the efficacy of transcranial low-level light/laser therapy (LLLT), for enhancing cognitive function in middle-aged and older adults and participants with Mild Cognitive Impairment.
Detailed description
The goal of this project is to test the efficacy of LLLT to enhance neurocognitive function in middle-aged adults and examine the modulating influences of carotid atherosclerosis. The specific aims will be accomplished in a randomized controlled trial (RCT) by examining cognitive test performance and blood oxygen level-dependent (BOLD) response to a working memory task in middle-aged and older adults and participants with Mild Cognitive Impairment pre- and post- six-week long intervention of LLLT or placebo. In addition, the investigators will examine if carotid artery intima-media thickness (IMT) moderates the therapeutic effects of LLLT.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | LLLT | The treatment will consist of applying light of a specific wavelength (1064 nm) using a laser diode supplied by Cell Gen Therapeutics, LLC (CG-5000 laser, HD Laser Center, Dallas, TX, USA). |
| DEVICE | Placebo | The treatment will consist of applying light of a specific wavelength (1064 nm) using a laser diode supplied by Cell Gen Therapeutics, LLC (CG-5000 laser, HD Laser Center, Dallas, TX, USA). However, the placebo group will receive approximately 1/12th of the cumulative energy density as the treatment group. |
Timeline
- Start date
- 2016-02-21
- Primary completion
- 2020-04-30
- Completion
- 2020-04-30
- First posted
- 2016-08-01
- Last updated
- 2023-10-04
- Results posted
- 2023-10-04
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT02851173. Inclusion in this directory is not an endorsement.