Clinical Trials Directory

Trials / Completed

CompletedNCT02848313

An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects With Intermediate Age-Related Macular Degeneration

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
40 (actual)
Sponsor
Stealth BioTherapeutics Inc. · Industry
Sex
All
Age
55 Years
Healthy volunteers
Not accepted

Summary

This is an open-label, Phase 1 single-center study in approximately 40 subjects who have 1 eye with intermediate AMD, including a high-risk drusen without geographic atrophy (GA) subgroup and a noncentral GA subgroup. Eligible subjects will receive 40 mg of elamipretide administered as a once daily 1.0 mL subcutaneous injection for 12 weeks.

Conditions

Interventions

TypeNameDescription
DRUGElamipretide40 mg dose of elamipretide administered once daily as a 1.0mL SC injection.

Timeline

Start date
2016-10-28
Primary completion
2018-03-16
Completion
2018-04-10
First posted
2016-07-28
Last updated
2020-10-20
Results posted
2020-09-21

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02848313. Inclusion in this directory is not an endorsement.