NCT02839421

Efficacy of Three Antibiotic Protocols for Aggressive Periodontitis Treatment

Efficacy of Moxifloxacin, Amoxicillin+Metronidazole for Aggressive Periodontitis Treatment

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: Facultad Nacional de Salud Publica · Academic / Other
• Sex: All
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The aim of the present study is to evaluate the clinical and microbiological efficacy of moxifloxacin or amoxicillin plus metronidazole in one-stage scaling and root planing in treating generalized aggressive periodontitis. Forty five subjects will be randomly allocated to 3 treatment groups. Subgingival plaque samples will be analysed for cultivable bacteria. The primary outcome variable to determine the superiority of one treatment over the others would be differences between groups for means CAL changes at 6 months post-treatment. Secondary outcome variables include differences between therapies for the mean changes in the mean levels of PD and the proportion of BOP.

Conditions

• Aggressive Periodontitis

Interventions

Type	Name	Description
DRUG	Scaling and Root Planing combined with moxifloxacin	Scaling and Root Planing combined with systemically administered moxifloxacin (MOX) 400 mg, once daily for 7 days

Timeline

• Start date: 2015-12-01
• Primary completion: 2019-05-31
• Completion: 2019-05-31
• First posted: 2016-07-21
• Last updated: 2019-05-29

Locations

1 site across 1 country: Colombia