NCT02837887

Computerized Cognitive Behavior Therapy in Treating Depression in Patients With Cancer

A Computerized Cognitive Behavioral Therapy for Cancer Patients With Major Depressive Disorder

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 31 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This randomized clinical trial studies how well a computerized cognitive behavior therapy program works in treating depression in patients with cancer. The cognitive behavior therapy program uses a series of internet-delivered sessions intended to help patients identify and change problematic patterns of thinking and behavior that maintain depression.

Detailed description

PRIMARY OBJECTIVES: I. Establish the efficacy of computerized cognitive behavior therapy ("Beating the Blues") in reducing symptoms of depression and remission of major depressive disorder (MDD) in cancer patients. II. Test the feasibility of implementation and patient acceptability of online computerized cognitive behavior therapy for cancer patients with major depressive disorder (MDD). III. Test moderators (cancer specific stress, MDD history, anxiety disorder comorbidity, and homework compliance) of treatment outcome. OUTLINE: Patients are randomized to 1 of 2 groups. GROUP I (IMMEDIATE TREATMENT): Patients undergo computerized cognitive behavior therapy consisting of 45-60 minute sessions once per week for 8 weeks. Patients also complete the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD7) at weeks 1, 3, 5, 7 and 8 and complete other questionnaires for 15-30 minutes each that assess psychosocial and physical symptoms. GROUP II (WAIT-LIST): Patients are placed on an 8-week wait-list and then undergo computerized behavior therapy and receive questionnaires as in Group I. After completion of study intervention, patients are followed up at 2, 4, and 6 months.

Conditions

• Major Depressive Disorder

Interventions

Type	Name	Description
BEHAVIORAL	Computerized Cognitive Behavior Therapy	Undergo computerized cognitive behavior therapy

Timeline

• Start date: 2016-07-15
• Primary completion: 2017-12-31
• Completion: 2018-03-29
• First posted: 2016-07-20
• Last updated: 2020-06-22

Locations

1 site across 1 country: United States